Small nerves.
Big pain.
Countless questions.

We have answers.

Corinthian Reference Lab (CRL) is a commercial diagnostic laboratory specializing in neurological disease detection, particularly small fiber neuropathy testing. CRL specializes exclusively in epidermal nerve fiber density (ENFD) testing.

ENFD testing offers medical practitioners and their patients objective evidence of a neuropathy which can hopefully lead to a more accurate diagnosis of the underlying cause.

Physicians choose CRL for our expertise in performing this very specific labor intensive test. Specimens require extensive manual manipulation and nerve fibers are counted manually. Each case is read by both a neuromuscular neurologist and dermatopathologist to provide the most specialized interpretations of the patient’s specimen. At Corinthian Reference Lab, we are committed to providing the most accurate diagnostic small fiber neuropathy testing available so that each patient ultimately receives the best possible care.

What is
small fiber neuropathy?

Small fiber peripheral neuropathy is a type of peripheral neuropathy that occurs from damage to the small unmyelinated peripheral nerve fibers, which are found in skin and organs. Although there are many possible causes of small fiber neuropathy, the most common is diabetes or glucose intolerance. Although symptoms of small fiber neuropathy vary widely, it’s usually first accompanied by pain such as burning, pins and needles, tingling and numbness, or in some cases an insensitivity to pain. Symptoms typically present first in the feet and progress upwards. Because small fiber neuropathy can be caused by a range of health conditions, it is first most important to objectively diagnose that the neuropathy exists and then run appropriate tests to diagnose the underlying etiology.

Meet The Physicians

David Saperstein, M.D. Neuromuscular Neurologist

David Saperstein, M.D., is a graduate of Boston University School of Medicine. He completed his Neurology residency at Wilford Hall USAF Medical Center in San Antonio, Texas, followed by a Neuromuscular Disease/Clinical Neurophysiology fellowship at the University of Texas Southwestern Medical Center in Dallas. Dr. Saperstein is board certified in Neurology, Neuromuscular Medicine and Electrodiagnostic Medicine. Dr. Saperstein participated in multicenter research studies of treatments for amyotrophic lateral sclerosis, myasthenia gravis, immune-mediated neuropathies, and muscular dystrophy. Dr. Saperstein has authored or co-authored over 40 journal articles, book chapters and abstracts regarding various aspects of nerve and muscle diseases like small fiber neuropathy. He is a Neuromuscular Neurologist for CRL.

Todd Levine, M.D. Neuromuscular Neurologist

Todd Levine, M.D., is a graduate of Duke University Medical School. He completed his internship in Internal Medicine at Jewish Hospital in St Louis. He completed his neurology residency at Barnes Hospital in St Louis. He finished a two-year fellowship in neuromuscular disease at Washington University in St Louis and is board certified in Neurology as well as Electrodiagnostic Medicine. He is Co-Director of the neurophysiology department at Banner Good Samaritan Medical Center. He also conducts extensive research in diseases of the nerve and muscle (like small fiber neuropathy) and continues to publish his findings in numerous peer reviewed journals. Dr. Levine also serves as a Neuromuscular Neurologist for CRL.

Mary E. Landau-Tennis, M.D. Medical Director

Mary E. Landau-Tennis, M.D., is triple board certified in Anatomic Pathology, Clinical Pathology, and Dermatopathology. She serves as the medical director of Corinthian Reference Laboratory. Dr. Landau graduated from Duke University Medical School and completed her Anatomic and Clinical Pathology Residency as well as her fellowship in Dermatopathology at Washington University in St. Louis. Her areas of small fiber neuropathy expertise include inflammatory and painful skin disorders, melanocytic lesions of the skin and medical illustration.