Small nerves.
Big pain.
Countless questions.

We have answers.

Corinthian Reference Lab (CRL) is a commercial diagnostic laboratory specializing in neurological disease detection, particularly small fiber neuropathy testing. CRL specializes exclusively in epidermal nerve fiber density (ENFD) testing. ENFD testing offers medical practitioners and their patients objective evidence of a neuropathy which can hopefully lead to a more accurate diagnosis of the underlying cause.
Physicians choose CRL for our expertise in performing this very specific labor intensive test. Specimens require extensive manual manipulation and nerve fibers are counted manually. Each case is read by both a neuromuscular neurologist and dermatopathologist to provide the most specialized interpretations of the patient’s specimen. At Corinthian Reference Lab, we are committed to providing the most accurate diagnostic small fiber neuropathy testing available so that each patient ultimately receives the best possible care.

What is small fiber neuropathy?

Small fiber peripheral neuropathy is a type of peripheral neuropathy that occurs from damage to the small unmyelinated peripheral nerve fibers, which are found in skin and organs. Although there are many possible causes of small fiber neuropathy, the most common is diabetes or glucose intolerance. Although symptoms of small fiber neuropathy vary widely, it’s usually first accompanied by pain such as burning, pins and needles, tingling and numbness, or in some cases an insensitivity to pain. Symptoms typically present first in the feet and progress upwards. Because small fiber neuropathy can be caused by a range of health conditions, it is first most important to objectively diagnose that the neuropathy exists and then run appropriate tests to diagnose the underlying etiology.